Breast Cancer Management and Outcomes in Regional Victoria (#325)
Objective: Breast cancer accounts for 28% of all new cancers in Australian Women1. Patients in regional areas historically have poorer outcomes compared to their metropolitan counterparts. We conducted a clinical audit on breast cancer patients treated at Goulburn Valley Health (GVH) Oncology Unit to describe their clinical presentations and timeliness of management.
Method: This is a retrospective study conducted at GVH Oncology Unit from 1st February 2012 to 30th September 2014. Approval was obtained from the GVH Ethics Committee.
Results:
A total of 191 patients with breast cancer of a median age 57 years (range 36 - 82) were identified from the electronic medical records. Majority (n=118) were newly diagnosed, nearly a quarter (n=45) had their care transferred to GVH and the remaining (n=28) developed recurrence. Only 28% (33) of newly diagnosed patients were detected through screening mammography. 77 percent presented with non-metastatic disease while 23% had stage 4 disease at diagnosis. Majority were referred by surgeons (54%), followed by physicians (17%), general practitioners (13%) and other specialists (16%).
Most patients with non-metastatic disease (93%) underwent definitive surgery - 63% were mastectomy; 7 bilateral mastectomies. The median time from biopsy to surgery is 21 days (n=124) while that from referral to first oncology appointment is 20 days (n=170). Nearly two thirds (n=123) received either chemotherapy and/or radiotherapy (n=117). The median time from biopsy to chemotherapy is 63 days (n=102), while that from surgery to chemotherapy is 46 days (n=83). 85% have endocrine positive disease while 18% have HER2-positive disease. Median overall survival of patients with stage 4 disease is 287 weeks (15-1260 weeks).
Conclusion: . Regional patients tend to be older at presentation, diagnosed at a more advanced stage and more often with metastatic disease. Median times will be further analysed. Overall survival is comparable to Statewide data.
- Australian Cancer Incidence and Mortality (ACIM) Books - Breast cancer for Australia (ICD10 C50). http://www.aihw.gov.au/acim-books/ [Accessed July 2015].
- Cancer Council Victoria – ‘CCV Statistic Trends 2013’. http://www.cancervic.org.au/downloads/cec/cancer-in-vic/CCV-statistics-trends-2013.pdf [Accessed July 2015]