Dr Paul James is a Clinical Geneticist in the Familial Cancer Centre at the Peter MacCallum Cancer Centre, Head of Adult Genetics at the Royal Melbourne Hospital and a Clinical Associate Professor in the Department of Medicine, Monash University. He leads a program of clinical research including discovery and translational projects emphasising familial cancer and the genetics of inherited cardiac disorders. He initiated and continues to lead the Variants in Practice (ViP) Study – a translational program to investigate genomic risk assessment in Victorian breast and ovarian cancer families.