A/Prof Dan Buchanan is Head of the Colorectal Oncogenomics Group in the Department of Clinical Pathology at the University of Melbourne, residing within the Victorian Comprehensive Cancer Centre. He leads a diverse, multi-disciplinary research program (>300 publications) aimed at improving the diagnosis of hereditary gastrointestinal cancer and polyposis syndromes and determining the aetiology of colorectal cancer and polyposis using integrative multi-omic and molecular pathology epidemiology approaches applied to world-leading studies. He holds an honorary appointment within the Genomic Medicine and Familial Cancer Centre, Royal Melbourne Hospital, contributing to a multidisciplinary approach to the diagnosis and risk management of hereditary cancer and colonic polyposis. He holds leadership roles as an InSiGHT council member, co-PI of the Colon Cancer Family Registry, and co-chair of the ClinGen-InSiGHT CRC-Polyposis Variant Curation Expert Panel for the POLE and POLD1 genes. He is a National Health and Medical Research Council of Australia Investigator Fellow and was awarded the Dean’s Research Excellence Award (Dame Kate Campbell Fellowship 2021-2025). He is committed to the translation of research to practice, evidenced by his role in the Australian eviQ Cancer Genetics Reference Committee tasked with providing national guidelines for testing and management of hereditary cancer syndromes. He is the PI of the Genetics of Colonic Polyposis Study, and PI of the ANGELS study investigating the aetiology of early-onset colorectal cancer.